1H-Indole, 4-Methyl-7-nitro-
4-Methyl-7-nitro-1H-indole
CAS: 289483-80-3
Molecular Formula: C9H8N2O2
1H-Indole, 4-Methyl-7-nitro- - Names and Identifiers
| Name | 4-Methyl-7-nitro-1H-indole |
| Synonyms | 4-Methyl-7-nitro-1H-indole 4-METHYL-7-NITRO-1H-INDOLE 4-methyl-7-nitro-1H-Indole 1H-Indole, 4-Methyl-7-nitro- 1H-indole, 4-methyl-7-nitro- 2-(p toluene sulphonyloxymethyl) 6-methyl 2,3-dihydro [4H] 1,4-benzodioxin |
| CAS | 289483-80-3 |
| InChI | InChI=1/C9H8N2O2/c1-6-2-3-8(11(12)13)9-7(6)4-5-10-9/h2-5,10H,1H3 |
1H-Indole, 4-Methyl-7-nitro- - Physico-chemical Properties
| Molecular Formula | C9H8N2O2 |
| Molar Mass | 176.17 |
| Density | 1.355 |
| Boling Point | 384.382°C at 760 mmHg |
| Flash Point | 186.268°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.694 |
1H-Indole, 4-Methyl-7-nitro- - Introduction
It is an organic compound. Its molecular formula is C9H8N2O2 and its relative molecular mass is 176.17g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Yellow to orange-yellow crystalline.
-Melting point: About 176-178 ° C.
-Solubility: Almost insoluble in water, slightly soluble in organic solvents such as ethanol, chloroform, etc.
Use:
-It can be used as raw materials for dyes and pigments, and used for coloring pigments, coatings, plastics, etc.
-It can also be used in the synthesis of pesticides, pharmaceuticals and other organic compounds.
Method: There are many synthesis methods of
-, one of the commonly used methods is obtained by nitration reaction and methylation reaction of indole. The specific steps are as follows:
1. Indole is reacted with nitric acid in the presence of sulfuric acid, and nitrated to obtain nitroindole.
2. Then react the obtained nitroindole with a methylating reagent (such as methyl copper iodide) to perform a methylation reaction to obtain pyridine.
Safety Information:
-is an organic compound, which has certain toxicity and should be handled with caution.
-Appropriate protective measures should be taken during operation, such as wearing protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated place.
-Avoid direct contact with skin, eyes and respiratory tract, and try to avoid inhaling its gas or dust.
-In case of skin contact or accidental inhalation, rinse immediately and seek medical assistance.
-in storage and handling, should be away from fire and oxidant, stored in a cool, ventilated place.
Nature:
-Appearance: Yellow to orange-yellow crystalline.
-Melting point: About 176-178 ° C.
-Solubility: Almost insoluble in water, slightly soluble in organic solvents such as ethanol, chloroform, etc.
Use:
-It can be used as raw materials for dyes and pigments, and used for coloring pigments, coatings, plastics, etc.
-It can also be used in the synthesis of pesticides, pharmaceuticals and other organic compounds.
Method: There are many synthesis methods of
-, one of the commonly used methods is obtained by nitration reaction and methylation reaction of indole. The specific steps are as follows:
1. Indole is reacted with nitric acid in the presence of sulfuric acid, and nitrated to obtain nitroindole.
2. Then react the obtained nitroindole with a methylating reagent (such as methyl copper iodide) to perform a methylation reaction to obtain pyridine.
Safety Information:
-is an organic compound, which has certain toxicity and should be handled with caution.
-Appropriate protective measures should be taken during operation, such as wearing protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated place.
-Avoid direct contact with skin, eyes and respiratory tract, and try to avoid inhaling its gas or dust.
-In case of skin contact or accidental inhalation, rinse immediately and seek medical assistance.
-in storage and handling, should be away from fire and oxidant, stored in a cool, ventilated place.
Last Update：2024-04-09 02:00:44
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CAS: 289483-80-3
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CAS: 289483-80-3
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